What happened on July 27th?

Treatment for diabetes comes to life

Good morning!

On this day in 1921, scientists achieved a breakthrough that changed the course of medicine: the successful isolation of insulin. This discovery brought hope to millions of people with diabetes, transforming lives and revolutionizing treatment options.

Here's what else happened on this day in history:

💉 1921: Scientists Successfully Isolated Insulin

In 1921, a significant breakthrough in medical science was achieved when Canadian scientists Frederick Banting and Charles Best successfully isolated insulin. Working in the laboratory of Professor John Macleod at the University of Toronto, Banting and Best's research focused on the pancreas and its role in diabetes. Their work built on previous studies that suggested a substance in the pancreas could regulate blood sugar levels.

Banting and Best experimented on dogs, removing the pancreas to induce diabetes and then injecting extracts of pancreatic tissue to observe the effects. They discovered that these extracts could lower blood sugar levels in diabetic dogs, effectively controlling the symptoms of diabetes. This substance, which they named insulin, was identified as the hormone responsible for regulating blood sugar.

Following their groundbreaking discovery, Banting and Macleod were awarded the Nobel Prize in Physiology or Medicine in 1923, which they shared with Best and biochemist James Collip, who helped purify insulin for human use. The successful isolation and application of insulin remain one of the most important milestones in medical history, saving millions of lives and paving the way for future research in endocrinology and diabetes care.

This photo shows Banting and Best with a dog that helped them in their experiments on the roof of the Medical Building, University of Toronto. The photo was taken by Henry Mahon in August 1921. The dog, although frequently identified as Marjorie (Dog 33) is actually Dog 408.

⚔️ 1214: The Battle of Bouvines Took Place  

The Battle of Bouvines took place in northern France, where the forces of King Philip II of France defeated an allied coalition of the Holy Roman Empire, England, and Flanders. This victory significantly strengthened the French monarchy and weakened the power of the feudal lords.

1794: The Thermidorian Reaction Took Place During the French Revolution

The Thermidorian Reaction marked a turning point in the French Revolution, leading to the fall of Maximilien Robespierre and the end of the Reign of Terror. Robespierre and his allies were arrested and executed. This paved the way for a more moderate phase of the revolution. Read more about the French Revolution in French Revolution: History, Timeline, Causes, and Outcomes.

1830: The July Revolution Began in France

In July 1830, the July Revolution, also known as the Second French Revolution, erupted in France in response to the repressive policies of King Charles X. The discontent was sparked by the king's July Ordinances, which dissolved the Chamber of Deputies, suspended the press, and restricted voting rights. This led to widespread protests and an uprising in Paris, where barricades were erected, and intense street fighting took place over three days, from July 27 to July 29. The revolution resulted in the abdication of Charles X and the establishment of the July Monarchy under Louis-Philippe, who promised to uphold a more liberal constitutional monarchy.

💔 1919: Chicago Race Riot Ignited

The Chicago Race Riot of 1919 erupted after an African American teenager was stoned and drowned for violating the unofficial segregation of Chicago's beaches. The riot lasted for several days, resulting in 38 deaths and hundreds of injuries, highlighting racial tensions in the United States.

🐰 1940: Warner Brothers Released the Looney Tunes

Warner Brothers released the first Looney Tunes animated short, which introduced iconic characters like Bugs Bunny, Daffy Duck, and Porky Pig. These characters became cultural icons and significantly influenced animation and popular culture.

✍️ 1953: Armistice Agreement Ending the Korean War Signed

The Korean Armistice Agreement was signed, effectively ending the Korean War. The agreement established the Korean Demilitarized Zone (DMZ) and ceased hostilities between North and South Korea, though a formal peace treaty was never signed.

🤦 1974: Impeachment of Nixon After the Watergate Scandal

The U.S. House of Representatives Judiciary Committee voted to recommend the first article of impeachment against President Richard Nixon for obstruction of justice related to the Watergate scandal. The scandal stemmed from the Nixon administration's attempt to cover up its involvement in the June 17, 1972, break-in at the Democratic National Committee headquarters at the Watergate office complex in Washington, D.C.  This eventually led to Nixon's resignation on August 8, 1974.

🌟 Born on This Day in History

1777: Thomas Campbell, British Poet

Thomas Campbell was a Scottish poet known for his sentimental and patriotic verse. His notable works include The Pleasures of Hope and Hohenlinden.

1922: Norman Lear, US Producer, Writer, and Director

Norman Lear is an American television writer and producer known for creating groundbreaking sitcoms such as All in the Family, The Jeffersons, and Good Times. His work often tackled social issues and helped shape modern television comedy.

💔 Died on This Day in History

1844: John Dalton, British Scientist

John Dalton was an English chemist, physicist, and meteorologist best known for his pioneering work in the development of modern atomic theory and his research on color blindness, now called Daltonism in his honor.

1946: Gertrude Stein, Writer

Gertrude Stein was an American novelist, poet, and art collector. She was a central figure in the Parisian avant-garde and is known for works such as The Autobiography of Alice B. Toklas and Tender Buttons.

We’ll talk this time tomorrow!

Matt